went and looked at your previous post, so its a 2000 srx,
now, have you inspected the wire from the cdi box going to the coil on that cylinder?
if thats good with no problems, you either have a issue with the p/v-cable set up, or the cdi box. With the 3d ign. susytem each plug is fired at its own time, so the only thing left is those 2 items that can cause the issue.
add: i would inspect the flywheel for rust on one of the magnets, you never replied back if you checked that????, it could cause a high rpm misfire if the 1 magnet is rusty, the signal would get weaker to the pick up coil as the rpm climbs if its rusty.